Biostimulator Treatments, Marylebone, London

With so many injectable treatments available today, choosing the right one for your skin can feel overwhelming, especially when it comes to collagen-stimulating injectables that offer more than just volume. Two of the most popular options are HArmonyCa and Radiesse, both of which deliver powerful rejuvenating effects, but in slightly different ways. So how do you choose between them? Let’s break down how each one works, what they’re best suited for, and how to know which might be the right fit for your skin goals.

Understanding collagen-stimulating injectables

Unlike traditional hyaluronic acid fillers that primarily add volume, biostimulatory injectables like HArmonyCa and Radiesse work by encouraging your skin to produce more collagen. Collagen is the protein that gives your skin its structure, firmness and elasticity, and sadly, it naturally declines as we age.

These injectables help rebuild that structure from within, improving not just how your skin looks today, but how it behaves in the months to come.

What is HArmonyCa?

HArmonyCa is one of the newest and most advanced injectables in this category, and it’s a treatment I personally use and recommend. It combines hyaluronic acid, which hydrates and plumps the skin immediately, with calcium hydroxyapatite microspheres, which stimulate collagen production over time. This makes it a dual-action treatment that delivers both instant and progressive results.

It’s particularly good for addressing early skin laxity and the thinning, crepey texture that starts to appear in your 40s and beyond. Think of it as a ‘structure and support’ treatment, refining contours, improving firmness, and leaving the skin visibly more resilient.

Where is HArmonyCa used?

I typically use HArmonyCa to treat areas like the cheeks, jawline and lateral face, places where we start to see subtle sagging or volume depletion, and where the skin needs that gentle lift and firmness. It’s also a great option for those who are noticing early changes in skin texture and want to restore that feeling of strength and bounce.

What about Radiesse?

Radiesse is another biostimulatory injectable made purely from calcium hydroxyapatite. It was one of the first collagen-stimulating fillers to gain popularity, and it’s still widely used in many clinics around the world.

It provides structure and lift and works well for areas like the jawline or hands, where more definition is needed. However, Radiesse doesn’t contain hyaluronic acid, which means it lacks the immediate hydrating and volumising effect of newer injectables like HArmonyCa. It’s also not reversible, which is something to consider if you’re newer to these treatments or want more flexibility in your results.

Why I prefer HArmonyCa in clinic

While Radiesse has its place, I believe HArmonyCa offers a more elegant, modern approach to skin rejuvenation. Its combination of hydration and collagen stimulation makes it incredibly versatile, and the results are both subtle and strengthening.

In my clinical experience, patients love that it improves both skin texture and structure without dramatically changing their appearance. It’s about restoring, not transforming, your natural contours in a way that looks effortless and natural.

Which treatment is right for you?

If you’re in your 40s, 50s or beyond and you’ve started to notice skin that feels thinner, less firm or just not quite as supported as it once was, HArmonyCa could be a fantastic option. It’s ideal for anyone looking to age well with treatments that enhance, not overpower, your natural features.

If you’re considering collagen stimulation but unsure where to start, book a consultation. I’ll take the time to assess your skin, explain your options in full, and design a treatment plan that aligns with your goals and skin health long term.