NAD supplementation, London

Menopause marks a major transitional phase in a woman’s life, bringing with it a host of physical and hormonal changes. One lesser-known aspect affected by menopause is the level of NAD+ in the body. NAD+, or Nicotinamide Adenine Dinucleotide, is a molecule essential to cellular energy production, metabolic function, and longevity. With menopause, NAD+ levels decline, impacting overall health and accelerating aspects of the ageing process. Understanding what NAD+ is, why it’s crucial for health, and how best to boost it can make a meaningful difference for women navigating menopause.

What is NAD+ and why is it Important?

NAD+ is a coenzyme found in all living cells and is vital for a variety of metabolic processes. It plays a central role in converting nutrients from food into energy, helping fuel cells’ day-to-day functions. Beyond energy production, NAD+ is involved in DNA repair, cellular signalling, and activating sirtuins, proteins that regulate cellular health and ageing. Essentially, NAD+ helps keep cells functioning optimally and prevents cellular deterioration, which is why it’s often associated with anti-ageing benefits.

As we age, however, our NAD+ levels naturally decline. Studies have shown that NAD+ levels can drop by as much as 50% by middle age and continue to fall as we get older. This decline affects mitochondrial function (the powerhouse of the cell) and reduces the cell’s ability to repair DNA, which can lead to increased cellular stress and faster biological ageing. For women, menopause accelerates this process due to a sudden drop in oestrogen, which is linked to cellular changes affecting NAD+ production.

The Impact of Menopause on NAD+ Levels

During menopause, oestrogen levels plummet, leading to several physiological changes that can affect cellular health. Oestrogen plays a role in maintaining NAD+ levels, as it helps regulate processes that support mitochondrial function and cellular repair. With the decline in oestrogen, there’s a corresponding decrease in NAD+, which exacerbates symptoms associated with ageing, such as fatigue, cognitive decline, and metabolic slowing. Reduced NAD+ levels can also impair the body’s ability to manage oxidative stress, leading to cellular damage and acceleration of the ageing process.

Moreover, menopause-related hormonal shifts can contribute to inflammation and increase oxidative stress, which further deplete NAD+ reserves. This drop in NAD+ can exacerbate menopausal symptoms, making women feel more tired, mentally foggy, and less resilient. Maintaining adequate levels of NAD+ during and after menopause can therefore be crucial for improving energy levels, supporting cognitive health, and protecting against the cellular aging process.

Boosting NAD+ Levels: What Works and What Doesn’t?

Given the essential role of NAD+ in health and ageing, it’s no surprise that there’s growing interest in boosting NAD+ levels. Numerous supplements and treatments claim to raise NAD+ levels, but the effectiveness of these methods varies significantly.

One of the most popular methods touted for increasing NAD+ is intravenous (IV) therapy, which delivers NAD+ directly into the bloodstream. Whilst this may seem attractive, unfortunately science doesn’t back up its efficacy. NAD+ is a large molecule which only functions when inside the cells, Unfortunately it cannot be absorbed from the blood stream into the cells, and so intravenous NAD+ infusions will have no biological effect, Furthermore for many, the cost and inconvenience are prohibitive. The same holds true for intramuscular injections of NAD+ or NAD+ ‘pens’ which have recently come to market.

Another approach people take is using NAD+ supplements, such as nicotinamide riboside (NR) or nicotinamide mononucleotide (NMN), both of which are NAD+ precursors. While these supplements may help to a degree, studies show that simply adding more NAD+ precursors does not always translate to higher NAD+ levels in cells. The body’s natural conversion processes are complex and often limited, which means taking these supplements may only provide marginal improvements at best.

Nuchido TIME+: A More Effective Way to Support NAD+ Levels

An innovative and effective way to boost NAD+ levels is with Nuchido TIME+, a supplement specifically formulated to restore and support NAD+ levels through a scientifically backed approach. Unlike typical NAD+ precursors, Nuchido TIME+ doesn’t simply add more building blocks to the body; instead, it works by activating the body’s natural NAD+ production pathways. This approach is particularly beneficial because it addresses the root cause of NAD+ decline, helping to enhance the body’s efficiency in making and recycling NAD+.

Nuchido TIME+ was developed by a team of scientists who studied the mechanisms behind NAD+ synthesis and degradation. Their research led to a formula that supports the body’s ability to replenish NAD+ more sustainably. By working at a cellular level to improve the efficiency of NAD+ production, Nuchido TIME+ offers a way to increase NAD+ levels in a way that is both effective and lasting. For women going through menopause, this can make a real difference in managing symptoms and supporting cellular health during this transformative stage of life.

Nuchido TIME+ offers a scientifically grounded, practical approach to NAD+ support, making it a promising option for women seeking to support their bodies through menopause and beyond. Boosting NAD+ may not be the only way to mitigate the effects of menopause, but it’s certainly a powerful tool in the quest for better health and longevity.

If you’d like to learn more about NAD+, or to enquire about purchasing Nuchido TIME+, click here.